Publications/Research Papers Archives

Preventing Chemical, Biological, Radiological and Nuclear Disaster

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Disasters involving Chemical, Biological, Radiological, and Nuclear (CBRN) materials pose significant threats to life, property, and the environment, undermining humanity and sustainable development. These threats are evolving rapidly due to technological advancements and changing political dynamics. Preparing India to address CBRN threats is a daunting challenge, as anticipating such incidents and mitigating their devastating effects […]

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Toxic blister agents: Chemistry, mode of their action and effective treatment strategies

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Since their use during the First World War, Blister agents have posed a major threat to the individuals and have caused around two million casualties. Major incidents occurred not only due to their use as chemical warfare agents but also because of occupational hazards. Therefore, a clear understanding of these agents and their mode of

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Modulation of pentose phosphate pathway augments the efficacy of 2-deoxy-D-glucose in COVID-19 management

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Scientists and clinicians around the world have been investigating various drug targets and potential therapeutics for COVID-19, the disease caused by SARS-CoV-2. On May 8, 2021, the Defence Research and Development Organisation (DRDO) announced that its anti-COVID-19 therapeutic application of the drug 2-deoxy-D-glucose (2-DG) had been approved by the Drug Controller General of India (DCGI).

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Computational screening approaches for investigating potential activity of phytoligands against SARS-CoV-2

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Coronaviruses (CoVs) are infectious agents from the family Coronaviridae, classified into four genera: alpha-CoV, beta-CoV, gamma-CoV, and delta-CoV. These viruses have a host-derived membrane envelope, a helical nucleocapsid, and positive-sense, single-stranded RNA that can initiate infection without the need for essential enzymes. Over the past two decades, CoVs have caused three major zoonotic outbreaks: Severe

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Science of the Total Environment: Development of magnetic nanoparticle assisted aptamer-quantum dot based biosensor for the detection of Escherichia coli in water samples

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Microorganisms are widely present in soil, food, and water. Recently, bacterial and viral diseases linked to water contamination have emerged as a global health concern. Contaminated water serves as a source of disease transmission, and a report from the Centers for Disease Control and Prevention (CDC) indicates that 60% of the global burden of diarrheal

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